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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T76766 | Mirvetuximab | M9346A | Antifolate |
Mirvetuximab (M9346A) is a novel folate receptor α (FRα) monoclonal antibody targeting anti-FOLR1 (folate receptor 1). Mirvetuximab soravtansine is often conjugated with platinum compounds or other compounds to form anti... | |||
T76720 | Farletuzumab | MORAb-003 | Antifolate |
Farletuzumab (MORAb-003) is a potent inhibitor of folate receptor-α (FRα). Farletuzumab is a humanized monoclonal antibody with a high affinity for FRα. Farletuzumab inhibits the growth of cells that overexpress FRα. Far... | |||
T69268 | BGC-638 | ||
BGC-638, an analogue of BGC-945, is a thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)–overexpressing tumors. | |||
T38490 | ONX 0801 trisodium | Idetrexedtrisodium,BGC 945 trisodium,CB300945trisodium | |
ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor. | |||
T12635L | Plevitrexed | BGC9331,ZD 9331 | Others |
Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is an orally active and effective thymidylate synthase (TS) inhibitor (Ki: 0.44 nM). Plevitrexed is used for gastric ca... | |||
T77908 | Farletuzumab ecteribulin | MORAb-202 | |
Farletuzumab ecteribulin (MORAb-202) is a highly cytotoxic antibody-drug conjugate (ADC) targeting human folate receptor alpha (FRA). This ADC comprises the humanized Farletuzumab antibody linked to Mal-PEG2-Val-Cit-PAB-... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00147 | FOLR1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
FOLR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 kDa and the accession number is P15328. | |||
TMPJ-00148 | FOLR1 Protein, Rhesus macaque, Recombinant (His) | Rhesus | HEK293 Cells |
FOLR1 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-38 kDa and the accession number is F7BP60. | |||
TMPK-00150 | FOLR1 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required ... |